Best Enzyme Drain Cleaner – Top 8 of 2021

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We read tons reviews, and put together a list of the most popular sellers. Check out the top Enzyme Drain Cleaner below.


SaleNo. 1
Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer...
93 Reviews
Green Gobbler ENZYMES for Grease Trap & Sewer - Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer...
  • RAPID DEGRADATION TECHNOLOGY. Green Gobbler Enzyme Drain Cleaner degrades fats, oils, greases, starches, proteins, cellulose, sludge, and...
  • REDUCE PUMP-OUT FREQUENCY. Enzyme Drain Cleaner reduces the frequency of costly septic tank pump outs when used regularly. Increases the...
  • TARGETS FOG, EVEN AS pH DECREASES. Green Gobbler Enzyme Drain Cleaner aids in the biological breakdown of organic material inside of drains...
  • ULTRA-FAST ODOR ELIMINATION. Green Gobbler Enzyme Drain Cleaner eliminates odors associated with drain lines, lift stations, sewers, septic...
  • GUARANTEED, OR YOUR MONEY BACK. Green Gobbler’s conscious creations are safer, stronger, and more effective than caustic chemicals. 30-day...
No. 2
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
36 Reviews
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
  • 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments
  • Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
  • Ideal for commercial properties, retail, and hospitality
  • Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
  • Non-corrosive, non-flammable, non-acidic, and non-caustic with a fresh mint scent
No. 3
ECOS Earth Friendly Products Earth Enzymes Drain Maintainer, 2lbs
  • Cuts through grease, protein & hair buildup
  • Made with enzyme power
  • Safer for people, pets & the planet
  • Non-corrosive, won’t damage pipes
  • Made in USA without dyes, parabens, phosphates or phthalates
No. 4
Zep Drain Defense Pipe Build-Up Remover 64 Ounces ZLDC648
  • Item Weight: 4.67 lb
  • Country of Origin: United States
  • Brand name: Zep
  • Item Dimensions: 18.0"L x 11.5"W x 14.3"H
No. 5
Bio-Clean Drain Septic Bacteria
1,104 Reviews
Bio-Clean Drain Septic Bacteria
  • LISTING IS FOR 1 TWO POUND CANISTER
  • Special combination of natural bacteria and enzymes that DIGESTS dead organic waste found in your plumbing system
  • Eliminates costly backups. Up to 100 Drain Treatments.
  • Environmentally friendly and safe.
  • Multi Purpose. Kitchen sinks, showers, bath tubs, garbage disposals, septic tanks & fields, cat litter pans, motor homes and much more!
No. 6
Biokleen Bac-Out Drain Cleaner - 32 Ounce - Deodorizes, Prevents Clogs, Eco-Friendly, Non-Toxic, Live Enzyme-Producing...
  • Prevent clogs, treats slow drains and eliminates tough odors
  • A unique blend of enzymes, live cultures, and plant extracts
  • Unique gel formula coats thoroughly
  • No acids, artificial fragrance or colors
  • Made in the USA
No. 7
Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White
241 Reviews
Flo-Kem 5195 Flo-Zyme Commercial Bio-Enzyme Drain Opener/Deoderizer with Pleasant Scent, 1 Gallon Bottle, Milky White
  • Heavy duty bio-enzyme formula for opening up tough clogged drains
  • Breaks down and liquifies suspended solids like fats, oils, greases and other proteins
  • Eliminates foul odors
  • Use to maintain drain traps, waste treatment plants and other drain systems
  • White milky emulsion with a pleasant scent
SaleNo. 8
Roebic K-97 Main Line Cleaner, Exclusive Biodegradable Bacteria Digests Paper, Fats, and Grease in Sewer and Septic...
  • PREVENTS CLOGS AND BACKUPS: Roebic K-97 Main Line Cleaner naturally breaks down waste such as paper, sludge, fats & grease to quickly...
  • BIODEGRADABLE BACTERIA FORMULA: Main Line Cleaner contains millions of specialized biodegradable waste degrading bacteria to powerfully and...
  • SAFE FOR ALL PLUMBING: K-97 treatment is safe on all pipes for any household and the environment to help keep your lines free of backups
  • IDEAL FOR LOW FLOW TOILETS: K-97 is indispensable in resolving the problems of sludge buildup due to the inefficiencies of "low flow"...
  • EASY TO USE: Simply shake well, pour 8 ounces into toilet, and flush (repeat for 4 consecutive days); Repeat four times a year, or as needed